CD8A and central nervous system cancer: Finally, using a murine model of glioma followed by intracranial injection of Δ10 3′-UTR ZIKV, we determined that the presence of ZIKV causes a significantly higher infiltration of CD8-expressing cells in the tumor in comparison to PBS (Figure S4D), supporting the idea that tumor-associated inflammation plays a critical role in driving T cell infiltration, consistent with our prior work.47