NUDT10 showed lower expression in tumor tissues than in normal tissues, and patients with high expression in tumor tissues had lower survival rates than those with low expression, consistent with similar reports(e.g., lung squamous cell carcinoma, Gastric Cancer, Clear Cell Renal Cell Carcinoma, Hepatocellular Carcinoma) in the literature [52–54].Subsequently, we conducted relevant biological experiments that confirmed its tumor-promoting function in CRC. This evidence concerns the gene NUDT10 and hepatocellular carcinoma.