ERBB2 and neoplasm: Similarly, no significant differences were observed in any semi-quantitative and quantitative parameters across pathologic prognostic factors (ER, PR, HR, and HER2 status, Ki-67 index, nuclear grade, tumor size, and lymph node status) or clinical factors (menopausal status) (all p > 0.05), except for significant differences in TTP between ER-positive and ER-negative (p = 0.04) and between HR-positive and HR-negative groups (p = 0.05).