Antibody panel for limbic (LGI1, CASPR2, NMDAR, AMPA‐R, GABA‐B R, DPPX) and paraneoplastic (Anti‐Hu [ANNA‐1], Anti‐Yo [PCA‐1], Anti‐Ri [ANNA‐2], Anti‐Ma2/Ta, Anti‐Amphiphysin, Anti‐CV2.1 [CRMP5], Anti‐Recoverin, Anti‐SOX1 [AGNA], Anti‐GAD65) encephalitis was investigated during the diagnostic process and found to be negative in all the patients. This evidence concerns the gene CDR2 and encephalitis.