Overall, the 96 TFs associated with RCC were enriched in several protein complexes including MLL3/4 (P = 4.3×10−5), SWI/SNF (P = 4.7×10−5), ATPase (P = 2.3×10−7), NCOR1 (P = 2.3×10−7) and PBAF (P = 2.3×10−7) among others, across different databases (Supplementary Table 2). This evidence concerns the gene KMT2C and renal cell carcinoma.