In summary, this meta‐analysis suggests that QE supplementation may exert beneficial effects on liver function and lipid metabolism in patients with MASLD, as evidenced by significant reductions in ALT, AST, GGT, DBil, Tche, LDL, and TG, along with an increase in HDL levels and a decrease in CRP levels. This evidence concerns the gene CRP and metabolic dysfunction-associated steatotic liver disease.