Univariate Cox regression analysis indicated that elevated levels of ABG, LAGE, SDBG, and CV, as well as a higher recurrence rate of AP, occurrence of WON, IPN, ARDS, and AKI, longer hospital stays, elevated IL-6, TG, Cr, BUA, HCT, PLT, and CRP, as well as the severity and etiology of AP, were all associated with an increased risk of 3-year probability of PPDM-A (Table 2). This evidence concerns the gene CRP and alkaline phosphatase measurement.