The top hit in the European stroke GWAS24 in the chr18q21 region is chr18:60668973 (rs111345592, AF = .75, β = −0.03, SE = 0.01, P = 2.78×10−4) with strong regional support with a group of other SNPs near the 3’ end of PHLPP1 (Figure 1D). This evidence concerns the gene PHLPP1 and stroke disorder.