Furthermore, In hepatocellular carcinoma, CXCL10/TLR4-mediated MMP14 activation promotes recruitment of monocytic myeloid-derived suppressor cells (MDSCs) after acute liver injury, fueling post-transplant HCC relapse, as evidenced by clinical data, animal studies, and cell-culture assays (150). The gene discussed is CXCL10; the disease is hepatocellular carcinoma.