TOP2A and neoplasm: Representative genes like CXCL5, CHI3L1, HGF, MKI67, and TOP2A indicate links to adaptive immunity, cell proliferation, and tumor immune modulation (Figure 11H), while cnmf_7 was enriched for Fc-gamma receptor–mediated phagocytosis (TYROBP, FCGR2A, FCGR2B), B cell activation (CD84, MS4A7), and chemokine receptor binding (CCL3, CCL4, CCL5, CXCL9).