Among its eight subunits, CCT4 (also known as CCTδ) participates in the proper folding of actin, tubulin, and various oncogenic proteins, for instance, the RNA-binding protein YB-1 was found to upregulate CCT4 translation, resulting in enhanced folding/stability of the mLST8 protein (a component of mTOR complexes) and consequently hyperactivation of mTOR signaling that supports tumor cell growth and survival (12–14). The gene discussed is CCT4; the disease is neoplasm.