In the drug‐target MR analyses, we attempted to evaluate effects of 15 lipid‐modifying targets on pancreatitis, namely, HMGCR, NPC1L1, PCSK9, APOB, LDLR, ABCG5, ABCG8, ACLY, ANGPTL3, MTTP, PPARA, PPARD, PPARG, APOC3, and LPL. The gene discussed is APOB; the disease is pancreatitis.