It should be noted that the dysregulation of splicing factor protein kinases, SRPKs, both in expression and activation, potentially contributes to various diseases, especially the development of cancer,15 and crucially contributes to cancer cell aggressiveness.21,22 Therefore, SRPKs might be the key molecules which play an important role in tumor progression in terms of splicing regulator dysregulation.23 This evidence concerns the gene WEE1 and neoplasm.