NOS2 and diabetes mellitus: From the result of molecular docking data, 1 has good interaction to with both of pro-inflammatory cytokines (iNOS, COX-2, TNF-α, IL-1β, and IL-6); transcription factors (Nrf2 and NF-κB), diabetes enzyme with binding energies of −6.4, −6.4, −5.0, −5.8, −6.1 kcal mol−1; −6.1, −6.6 kcal mol; and −6.4 kcal mol−1, respectively, resulted that 1 is the promising candidate for anti-inflammatory and α-glucosidase inhibition.