NR3C1 and asthma: The heatmap reveals distinct immunomodulatory roles for core asthma targets: NR3C1 exhibits strong positive correlations with regulatory immune cells—notably memory B cells (r ≈ 0.64) and T follicular helper cells (r ≈ 0.48)—suggesting its role in enhancing immunosuppressive responses, consistent with its function as the glucocorticoid receptor.