As expected, PV patients had higher plasma lyso-Gb3 levels compared to LBV patients (p < 0.0001), increased septum thickness (p = 0.0056), serum NT-proBNP levels (p = 0.0489), and left ventricular mass (p = 0.008), resulting in a higher frequency of left ventricular hypertrophy (p = 0.027; Table 1) Noteworthy, the distribution of the main cardiac risk factors including diabetes, hypertension, and smoking showed no significant differences between both groups (Table 1). Here, NPPB is linked to Hypertension.