Increased expression of Lrrk2 is of particular note, especially in light of recent reports indicating that AD patient‐derived iPSC astrocytes harboring the G2019S LRRK2 mutation, associated with increased kinase activity, display a pro‐inflammatory phenotype as well as a decreased ability to promote angiogenesis (de Rus Jacquet et al. 2023). This evidence concerns the gene LRRK2 and Alzheimer disease.