Additionally, Connexin32 (Cx32) is a gap junction protein enriched at SLIs and essential for myelin integrity, as mutations in the gene encoding this protein (GJB1) cause CMT Type 1X (CMT1X) (Scherer et al. 1998; Balice‐Gordon et al. 1998; Bergoffen et al. 1993). This evidence concerns the gene GJB1 and X-linked Charcot-Marie-Tooth disease type 1.