Motivated by these structural insights and building on prior qualitative reports demonstrating that the organization of E‐Cadherin, MAG and Kv1.1 are altered in myelin from PMP22+/− and PMP22–/− mice (Guo et al. 2014; Neuberg et al. 1999), we employed high‐resolution confocal imaging and quantitative analysis of teased peripheral nerve fibers from constitutive CMT1A and HNPP model mice. Here, MAG is linked to hereditary neuropathy with liability to pressure palsies.