Motivated by these structural insights and building on prior qualitative reports demonstrating that the organization of E‐Cadherin, MAG and Kv1.1 are altered in myelin from PMP22+/− and PMP22–/− mice (Guo et al. 2014; Neuberg et al. 1999), we employed high‐resolution confocal imaging and quantitative analysis of teased peripheral nerve fibers from constitutive CMT1A and HNPP model mice. The gene discussed is KCNA1; the disease is hereditary neuropathy with liability to pressure palsies.