AFP and neoplasm: Plasma tumor biomarker profiling demonstrated AFP positivity in 2 cases, elevated CEA (>7 U/L) in 3 cases, CA125 (>35 U/L) in 1 case, CA19-9 (>37 U/L) in 8 cases, and CA72-4 (>7 U/L) in 1 case, highlighting the heterogeneity of biomarker expression in this resectable CCA population.