Hormone receptor status also shapes splicing: in ER+ breast cancer, the PML1 isoform cooperates with WDR5 to regulate stemness‐related genes such as YAP1, driving proliferation, invasion, and stem‐like traits [271], while splicing factors including FMRP [272] and RAVER1 [273] modulate ferroptosis and miRNA pathways. Here, SNIP1 is linked to breast carcinoma.