In muscular disorders, ASOs inducing exon skipping in Duchenne muscular dystrophy create PTCs, triggering transcriptional adaptation and compensatory utrophin upregulation [15], while hnRNPs contribute to limb‐girdle muscular dystrophy, myotonic dystrophy type 1 (DM1), oculopharyngeal muscular dystrophy, sporadic inclusion body myositis, multisystem proteinopathy, and spinal muscular atrophy (SMA) [345]. Here, UTRN is linked to myotonic dystrophy type 1.