USP36, USP37, USP47, and OTUD6B exert its oncogenic effects by stabilizing key oncoproteins, such as cellular myelocytomatosis oncogene (c-Myc), 14-3-3γ, Snail, and β-catenin, thereby promoting cancer cell proliferation, migration, and invasion 27-32. The gene discussed is OTUD6B; the disease is cancer.