As previous studies have demonstrated that members of the GPI-T play essential roles in the occurrence and development of malignancies, we compared the transcript levels of five GPI-T subunits (GPAA1, PIGK, PIGS, PIGT, and PIGU) between tumor and normal tissues using two independent datasets, GSE23036 and TCGA/HNC. The gene discussed is PIGU; the disease is neoplasm.