Trpm8 deletion or ablation of TRPM8‐expressed neurons abolishes nitroglycerin‐induced migraine‐like pain in mice, and the selective TRPM8 antagonist 1‐phenylethyl‐4‐(benzyloxy)‐3‐methoxybenzyl (2‐aminoethyl) carbamate (PBMC) also shows similar effects [81]. Here, TRPM8 is linked to migraine disorder.