TRPV1 and Alzheimer disease: Microglia derived from induced pluripotent stem cells of APOE ε4 (a genetic risk factor for sporadic AD)‐bearing AD patients exhibit overactivation and overproduce cholesterol, boosting major histocompatibility complex II (MHC II)‐dependent antigen presentation, which can be reversed by the TRPV1 agonist capsaicin [111].