FTH1 and malignant colon neoplasm: This concept is supported by emerging evidence; for instance, M2‐polarised macrophages can deliver ferritin heavy chain 1 to colon cancer cells via exosomes, which sequesters intracellular free iron and thereby confers ferroptosis resistance,58 and conversely, ferroptosis‐stressed cancer cells can release factors such as oncogenic KRAS protein, which are then taken up by macrophages to drive M2 polarisation via STAT3 signalling.59