SLC7A11 and hepatocellular carcinoma: In hepatocellular carcinoma, exosomal circUPF2 was found to enhance sorafenib resistance by forming a ternary complex with IGF2BP2 and SLC7A11 mRNA, stabilising SLC7A11 and suppressing ferroptosis independent of m6A modification,51 suggesting IGF2BP2 may employ both m6A‐dependent and ‐independent mechanisms to regulate ferroptosis, depending on cellular context and binding partners.