Using NGS + Sanger sequencing, the index patient was found to carry the pathogenic variant MYH7 c.748A > T (MYH7:p.Ile250Phe het) associated with HCM and also carried a rare variant DES c.553G > A (DES:p.Asp185Asn het) – a variant reported to be potentially associated with autosomal dominant dilated cardiomyopathy (DCM) type 1I,[3] though its causal role in DCM remains unconfirmed. The gene discussed is MYH7; the disease is autosomal dominant dilated cardiomyopathy.