In patients with acute pancreatitis admitted to the intensive care unit, Kaplan–Meier analysis showed that while higher serum iron and log2-ferritin were linked to increased all-cause mortality at all time points (in-hospital, 30, 90, and 365 days), lower transferrin and TIBC were associated with increased all-cause mortality only at the 30, 90, and 365-day follow-ups (log-rank P < .001). This evidence concerns the gene TF and acute pancreatitis.