AKT1 and hepatocellular carcinoma: The results of molecular docking further verified that quercetin, the active ingredient of Yinchen, has good binding activity when interacting with BIRC5.[152] Pan[147] found that the active ingredients quercetin and wedelolactone of Ecliptae herba inhibited the PI3K-AKT signaling pathway, thereby inhibiting the proliferation of HCC cells and promoting HCC cell apoptosis.