Although not significant, clinical sample analyses indicated that high TFAM expression is potentially associated with poor prognosis in liver cancer and pancreatic cancer (as reported in the Human Protein Atlas, https://www.proteinatlas.org/ENSG00000108064-TFAM/cancer/liver+cancer#LIHC_validation; https://www.proteinatlas.org/ENSG00000108064-TFAM/cancer/pancreatic+cancer#PAAD_TCGA). Here, TFAM is linked to digestive system neoplasm.