CD274 and neoplasm: Although no significant correlation was observed between sEV PD-L1 levels and statin intake in the entire population of tumor PD-L1-positive (tumor proportion score [TPS] ≥ 1%) patients (p = 0.657), a significant inverse correlation between sEV PD-L1 and statin intake was observed in patients with high tumor PD-L1 levels (TPS ≥ 50%).