(D) Schematic of infection of WT and Il27–/– mice for E and F. (E) Numbers of LTHSCs and granulocyte progenitors (GPs) (CD3−, NK1.1−, B220−, CD117+, CD34+, CD16/32hi, Ly6C+, CD135−, CD115−) in the bone marrow of WT and Il27–/– infected mice throughout infection. The gene discussed is CSF1R; the disease is infection.