To further elucidate the relationship between target genes and the outcome of HPV+ HNSCC, an analysis using Timer 2.0 revealed that only low expression levels of CCND1 and PXDN were associated with a favorable prognosis for HPV+ HNSCC (Figure 6E, Supplementary Figure S12D). The gene discussed is CCND1; the disease is head and neck squamous cell carcinoma.