1. Gut microbiota: ↑ α diversity in bleomycin models, ↑ beneficial bacteria (Lactobacillus, Bifidobacterium), ↓ pro-inflammatory bacteria; 2. gut-lung axis: Alleviates lung inflammation/fibrosis (plus TLR4/NF-κB inhibition). The gene discussed is NFKB1; the disease is inflammatory response.