CAPN14 and neoplasm: Heatmap analysis revealed that CAPN14 was mainly highly expressed in malignant cells and certain immune cell subsets, while THAP10 showed relatively higher expression levels in Tregs and proliferative T cells (Tprolis), suggesting that these two genes may play different biological functions in the formation and maintenance of the tumor microenvironment (Figures 7a, 7b, 7c, 7d, and 7e).