Additionally, among the list of TRPM7 interaction partners identified by Bai et al. that are not enlisted in BioGRID database, only IRAK1 (ProteinPrompt score = 0.77) belongs to the predicted list of TRPM7 interactors, suggesting a potential mechanistic link between TRPM7 and Toll-like receptor (TLR)/Interleukin-1 receptor (IL-1R) signaling pathway in cancer cells. The gene discussed is IRAK1; the disease is cancer.