Expression analysis of key regulators of cell migration (CXCR3, CCR7, CXCR5 and ITGAL, which encodes LFA1, an alias protein name) within these groups revealed significant upregulation of CCR7 in a subset of tumor-infiltrating SH2D2A-positive T cells and CXCR3 in infiltrating SH2D2A-positive T cells (Supplementary Figure 2C). Here, CCR7 is linked to neoplasm.