Compared to other EC subtypes,EC4 exhibited elevated expression levels of multiple genes implicated in antigen presentation (HLADRB1,HLA-DRB5,and HLA-DRA),immune cell recruitment (SELP,LIFR, and ACKR1),and anti-tumor inflammation (CCL14,IFITM1) (Figure 2d). The gene discussed is HLA-DRA; the disease is neoplasm.