1. Ginsenoside Rg3 improved cardiac function and infarct size in mouse with MI/RI. 2. Increased the expression of the ferroptosis-related protein GPX4 and inhibited iron deposition in mouse with MI/R injury.3. Attenuate OGD/R-induced ferroptosis in H9C2 cells. The gene discussed is GPX4; the disease is myocardial infarction.