1.CoQ10 supplementation promotes earlyrecovery of cardiac function in MI patients post PCI.2. Single CoQ10 treatment alleviates adversecardiac remodeling in response to experimental MI.3. CoQ10-treated macrophages exhibit a lessinflammatory state and suppressed activationof the NLRP3/IL1β pathway.4. CoQ10 mitigates post-infarction cardiacinflammation associated with IL1β signaling. Here, NLRP3 is linked to infarction.