MBP and MOG densities were statistically higher in the cKO relative to WT (Fig. 5 A,B,C, MBP p=0.005; MOG, p= 0.003) and in the AD/cKO relative to AD (Fig. 5 A,B,C, MBP, p=0.0004 and MOG, p=0.014). This evidence concerns the gene MBP and Alzheimer disease.