Ferraiuolo Ferraiuolo L. L. Dysregulation of astrocyte–motoneuron cross-talk in mutant superoxide dismutase 1-related amyotrophic lateral sclerosis Dysregulation of astrocyte–motoneuron cross-talk in mutant superoxide dismutase 1-related amyotrophic lateral sclerosis . The gene discussed is SOD1; the disease is amyotrophic lateral sclerosis.