IDET modulates various molecular targets, including NF‐κB, PI3K/AKT/mTOR, Wnt/β‐catenin, STAT3, and MAPK, thereby influencing processes such as apoptosis, autophagy, cell cycle regulation, and cell survival, which in turn affect tumor progression (Mehmood and Muanprasat 2022). This evidence concerns the gene NFKB1 and neoplasm.