In terms of mechanism, studies have shown that copper death can cause tumor cells to release damage-related molecular patterns (DAMPs), such as mitochondrial DNA, which in turn activate the cGAS-STING signaling pathway and promote the secretion of inflammatory factors such as type I interferons (IFNB) and chemokines (such as CXCL10). This evidence concerns the gene IFNB1 and neoplasm.