VWF and alkaline phosphatase measurement: As confirmed by the results of the present study, coagulation dysfunction is evident in AP, and the relevant laboratory indicators can be used to predict the progression of the disease at an early stage.13 In this study, PASS score, vWF:Ag, PT and D-D were substantially increased compared with the control group, whereas PLT, ATIII and Ca revealed considerable decreases (P < 0.001).