CCL2 and periodontitis: Pregnant women with poor periodontal parameters often exhibit increased levels of IL-1β and IL-8, resulting in premature uterine contractions that will result in premature labor.17,45 Raised sICAM-1 levels were found in those pregnant women who had periodontitis as well as preeclampsia.53 Another similar study claimed that sICAM-1 and sVCAM-1 could be considered clinical biomarkers for preterm birth.54 Molvarec et al., in the year 2013 on the same lines, reported the same findings along with the raised levels of IP-10, VCAM-1 and MCP-1 in preeclamptics compared to normotensives.55