RENBP and factor V deficiency: Severe Factor V deficiency in a 12-years old CHD patient with intracranial bleeding has been described by Ozkaya H et al.21 The raised von Willebrand factor antigen (vWF:Ag) as a marker of endothelial dysfunction has been revealed by Ismail and co-workers.22 In our study, Factor X and VII deficiency in one TOF patient is indicating towards defective formation of Vitamin-K dependent clotting factors, which is likely to be associated with compromised cardiac output and chronic liver congestion as mentioned by Zabala LM et al.17