More recently, in bleomycin-induced pulmonary fibrosis, hyaluronidase-functionalized luteolin nanoparticles (Lut@HAase) enabled targeted lung delivery, reduced collagen deposition and transforming growth factor-β1 (TGF-β1) expression, suppressed inflammation, improved lung function, and prolonged survival (Pan et al., 2024). This evidence concerns the gene TGFB1 and pulmonary fibrosis.