Improve cardiac function in zebrafish by regulating oxidative stress, inflammatory response and apoptosis-related pathwaysSTR, AR and GRR, as well as A-STR (total Alkaloids from STR), F-AR (total Flavonoids from AR) and F-GRR (total Flavonoids from GRR) also have excellent anti-heart failure activity. nppa↓, il1b↓, il6↓, tnfa↓, caspase 1↓, caspase3↓. This evidence concerns the gene AR and heart failure.