These findings are according to the study that evaluated the PRM2 mRNA levels in fertile and infertile men and found higher levels, but with no statistical difference in fertile men (Aoki et al., 2006), and agree to Avendaño et al. (2008) that found no differences in PRM2 mRNA between the fertile men groups in comparison to the infertile ones and also agree from studies that could not find any difference in PRM2 mRNA level among the analyzed groups (Steger et al., 2003; Ganguly et al., 2013). The gene discussed is PRM2; the disease is Infertility.