Completed. At 6 months: TG ↓ 43.5% (80 mg; p=0.0009) and 22.4% (50 mg; p=0.0775). At 12 months: TG ↓ 59.4% (80 mg; p=0.0002) and 43.8% (50 mg; p=0.0044). ApoC-III ↓ 73.7% (80 mg) and 65.5% (50 mg). Pancreatitis: 1 (80 mg), 1 (50 mg) vs 11 (placebo). No platelet drop <50k. Favorable tolerability. This evidence concerns the gene APOC3 and pancreatitis.