Search terms included “olezarsen,” “IONIS-APOCIII-LRx,” “APOC3-LRx,” “Tryngolza,” “apolipoprotein C-III,” “APOC3,” “familial chylomicronemia syndrome,” “severe hypertriglyceridemia,” “volanesorsen,” and “plozasiran” or “ARO-APOC3,” combined using Boolean operators (AND/OR). The gene discussed is APOC3; the disease is hypertriglyceridemia.