Hb: hemoglobin; ANC: absolute neutrophil count; MRD: measurable residual disease; CR: complete remission; CNV: copy-number variation; neg: negative; MPAL: mixed-phenotype acute leukemia; AML-M4: acute myelomonocytic leukemia; Hyper-CVAD: hyperfractionated cyclophosphamide, vincristine, doxorubicin, and dexamethasone; FISH: fluorescence in situ hybridization. The gene discussed is GSTM1; the disease is acute leukemia.