CRP and Sepsis: Stocker et al. Switzerland, conducted a secondary analysis of theNeonatal Procalcitonin Intervention Study (NeoPInS) to develop a machine learning model for predicting neonatal early-onset sepsis.Using a random forest algorithm on data from 1,685 neonates across multiple international centers, they found that biomarkersparticularly CRP and white blood cell count (WBC) were far more predictive than clinical signs or risk factors.