A prospective cohort analysis of 23,324 individuals in April 2021 found that vaccinatedpatients were 13% asymptomatic and 40% symptomatic, compared to 5% and 63% for the unvaccinated group [12].In our study, hypertension (41.6%) was the most common co-morbidity, possibly due to SARS-CoV-2 binding on ACE-2 receptors, which raisesangiotensin ll and stimulates RAAS, causing increased inflammation due to increased use of ACE inhibitors as anti-hypertensivemedication. This evidence concerns the gene ACE and hypertensive disorder.